Methotrexate-associated Lymphoproliferative Disorders:
نویسندگان
چکیده
منابع مشابه
Large ulceration of the oropharynx induced by methotrexate-associated lymphoproliferative disorders.
We present a case of a 67-year-old Japanese man with a serious oropharyngeal ulceration that at first seemed to be destructive malignant lymphoma or oropharyngeal carcinoma. We suspected methotrexate (MTX)-associated lymphoproliferative disorder (LPD) induced by MTX treatment for rheumatoid arthritis (RA). About 3 weeks after simple discontinuation of MTX, complete regression of the disease was...
متن کاملClinicopathological characteristics and rituximab addition to cytotoxic therapies in patients with rheumatoid arthritis and methotrexate-associated large B lymphoproliferative disorders.
AIMS To analyse the clinicopathological characteristics and prognosis of 40 rheumatoid arthritis (RA) patients with methotrexate (MTX)-associated large B cell lymphoproliferative disorders (MTX-BLPD). METHODS AND RESULTS Soluble interleukin 2 receptor titres (median 1500 U/ml) in 40 patients with MTX-BLPD were lower than those of 24 RA patients with non-MTX- associated (non-MTX) BLPD (5731 U/...
متن کاملClinicopathological analysis of methotrexate‐associated lymphoproliferative disorders: Comparison of diffuse large B‐cell lymphoma and classical Hodgkin lymphoma types
Patients with rheumatoid arthritis often develop methotrexate-associated lymphoproliferative disorders (MTX-LPD) during MTX treatment. MTX-LPD occasionally regresses spontaneously after simply discontinuing MTX treatment. In patients without spontaneous regression, additional chemotherapy is required to avoid disease progression. However, the differences between spontaneous and non-spontaneous ...
متن کاملHiv-Related Lymphoproliferative Disorders
Lymphoproliferative disorders including non-Hodgkin lymphomas (NHL) are not uncommon neoplasms in patients infected with the human immunodeficiency virus (HIV). It has been established that HIV-infected individuals are more prone to develop certain lymphoproliferative disorders and lymphomas compared to non-infected individuals. The exact mechanisms underlying these associations is yet to be es...
متن کاملEBV-associated lymphoproliferative disorders misdiagnosed as Crohn's disease.
Epstein-Barr virus (EBV) plays an etiological role in various diseases. EBV-associated lymphoproliferative disorder (LPD) is usually observed in individuals with congenital or acquired immune deficiencies but was also recently reported in non-immunocompromised individuals. Two cases of immunocompetent patients with EBV-associated T-cell LPD of the small bowel and colon who were initially misdia...
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ژورنال
عنوان ژورنال: The Kitakanto Medical Journal
سال: 2021
ISSN: 1343-2826,1881-1191
DOI: 10.2974/kmj.71.59